Olfactory Receptor family 52 subfamily I member 2.
Sequence:
10 20 30 40 50 60 70 80 90 100 MCQQILRDCI LLIHHLCINR KKVSLVMLGP AYNHTMETPA SFLLVGIPGL QSSHLWLAIS LSAMYIIALL GNTIIVTAIW MDSTRHEPMY CFLCVLAAVD 110 120 130 140 150 160 170 180 190 200 IVMASSVVPK MVSIFCSGDS SISFSACFTQ MFFVHLATAV ETGLLLTMAF DRYVAICKPL HYKRILTPQV MLGMSMAITI RAIIAITPLS WMVSHLPFCG 210 220 230 240 250 260 270 280 290 300 SNVVVHSYCE HIALARLACA DPVPSSLYSL IGSSLMVGSD VAFIAASYIL ILKAVFGLSS KTAQLKALST CGSHVGVMAL YYLPGMASIY AAWLGQDVVP 310 320 330 340 350 LHTQVLLADL YVIIPATLNP IIYGMRTKQL RERIWSYLMH VLFDHSNLGS
Transmembrane Helices:
TMR1 TMR2 TMR3 TMR4 TMR5 TMR6 TMR7 S Q L G F A S F S M P V P D A T H L P L H S I S V T F C W S L P L S S Y I S A L V Q I A L W M K P V F F M Q T I A I L S Y M G P L D A L S L S V S S L H V I I A R S S G L Y Y L I V Y I Y M A A M V I V A T A I T I G V M L A M V T A P I L A I D V A G T E A M S M V D S G V H S P N L T N G L A L V C T L L L G L M A I F A G C T G Y I I V I I L F C F A M V Q P T Y S A S L A K R M W I A T Y M P E V Y R D L I L I L Q A C I A V A K T K S S K G F UniProt | I-TASSER | AlphaFold | HORDE | GeneCards | ORDB
| Odorant | EC50 | Adjusted Top | Antagonist? | Aroma Notes |
|---|---|---|---|---|
| delta-decalactone | - | 5 1 | coconut, creamy, dairy, fatty, fresh, fruity, lactonic, milky, oily, peach, sweet | |
| decanal | -2.66 2 | 0.2141 2 | sweet, aldehydic, waxy, orange_peel, citrus, floral | |
| butyric acid | - | 0.4167 1 | sharp, acetic, cheesy, buttery, fruity, dairy, creamy | |
| diacetyl | - | 0 1 | buttery, caramellic, creamy, pungent, sweet |
1.) Geithe, C.; Andersen, G.; Malki, A.; Krautwurst, D. A butter aroma recombinate activates human class-I odorant receptors. J. Agric. Food Chem. 2015, 63, 9410–9420.
2.) Mainland JD, Li YR, Zhou T, Liu WL, Matsunami H. Human olfactory receptor responses to odorants. Sci Data. 2015 Feb 3;2:150002. doi: 10.1038/sdata.2015.2. PMID: 25977809; PMCID: PMC4412152.