decanoic acid

SMILES:
CCCCCCCCCC(=O)[O-]

Aroma Description:
citrus, fatty, rancid, sour1

Receptor log10 EC50 Adj. Top Antagonist? Correlated Perceptual Qualities
OR2W1 -3.76 4 9.8 4, 0 8  fatty, sweet, herbal, cucumber, orange, tart, mimosa, spicy, coumarinic, passionfruit
OR56A5 -4.4 7 5.3 7  rancid, cheesy, buttermilk, sweaty, sour
OR1G1 - 5.8376 2  waxy, tart, orange, sweet, aldehydic, fresh, citrus, clean, medicinal, anise
OR52B2 -4.28 7 1.2 7  rancid, cheesy, sour, juicy, tart
OR51E1 - 0 3, 0 4, 3.51 5  cheesy, sweaty, sour, acidic
OR52D1 - 0.2538 2  anise, cheesy, orange, sweet, dairy, sour, rancid, waxy, tart, sharp
OR10J5 - 0 4   
OR1A1 - 0 4   
OR2C1 - 0 4   
OR2J2 - 0 4   
OR51L1 - 0 4   
OR5P3 - 0 4   
OR51E2 - 0 6   
 

decanoic acid

SMILES:
CCCCCCCCCC(=O)[O-]

Aroma Description:
citrus, fatty, rancid, sour

Receptor Dock Score Affinity A100 Correlated Perceptual Qualities
OR51E1 0 0 (unknown)  
OR51E2 0 0 (unknown)  

Dock Score: This is a measure of whether the algorithm thinks the odorant is an agonist of the receptor.
Affinity: The binding affinity, in kJ/mol, of the ligand docked in the active or inactive model, whichever is greater.
A100: A measure of the degree of activation of the receptor. See Ibrahim et al (2019).

1.) The Good Scents Company

2.) Guenhael Sanz, Claire Schlegel, Jean-Claude Pernollet and Loic Briand Comparison of Odorant Specificity of Two Human Olfactory Receptors from Different Phylogenetic Classes and Evidence for Antagonism Chemical Senses vol. 30 no. 1 (2005) doi:10.1093/chemse/bji002

3.) YOSHIFUMI FUJITA, TOMOKO TAKAHASHI, AKIKO SUZUKI, KAYO KAWASHIMA, FUTOSHI NARA & RYUTA KOISHI (2007) Deorphanization of Dresden G Protein-Coupled Receptor for an Odorant Receptor, Journal of Receptors and Signal Transduction, 27:4, 323-334, DOI: 10.1080/10799890701534180

4.) Saito H, Chi Q, Zhuang H, Matsunami H, Mainland JD. Odor coding by a Mammalian receptor repertoire. Sci Signal. 2009 Mar 3;2(60):ra9. doi: 10.1126/scisignal.2000016. PMID: 19261596; PMCID: PMC2774247.

5.) Halperin Kuhns, V. L., Sanchez, J., Sarver, D. C., Khalil, Z., Rajkumar, P., Marr, K. A., & Pluznick, J. L. (2019). Characterizing novel olfactory receptors expressed in the murine renal cortex. American Journal of Physiology-Renal Physiology, 317(1), F172-F186.

6.) Christian B. Billesbølle, Claire A. de March, Wijnand J. C. van der Velden, Ning Ma, Jeevan Tewari, Claudia Llinas del Torrent, Linus Li, Bryan Faust, Nagarajan Vaidehi, Hiroaki Matsunami, Aashish Manglik. Structural basis of odorant recognition by a human odorant receptor. bioRxiv 2022.12.20.520951; doi: https://doi.org/10.1101/2022.12.20.520951

7.) Chatelain Pierre, Veithen Alex, Olfactory Receptors involved in the perception of sweat carboxylic acids and the use thereof. WO 2014/191047

8.) Franziska Haag, Antonella Di Pizio, Dietmar Krautwurst, The key food odorant receptive range of broadly tuned receptor OR2W1. Food Chemistry 375 (2022) 131680