Olfactory Receptor family 14 subfamily J member 1.
Estimated Expression: 88% of the population.
Expression estimate based on data from Verbeurgt et al (2014).
Sequence:
10 20 30 40 50 60 70 80 90 100 MVNLTSMSGF LLMGFSDERK LQILHALVFL VTYLLALTGN LLIITIITVD RRLHSPMYYF LKHLSLLDLC FISVTVPQSI ANSLMGNGYI SLVQCILQVF 110 120 130 140 150 160 170 180 190 200 FFIALASSEV AILTVMSYDR YAAICQPLHY ETIMDPRACR HAVIAVWIAG GLSGLMHAAI NFSIPLCGKR VIHQFFCDVP QMLKLACSYE FINEIALAAF 210 220 230 240 250 260 270 280 290 300 TTSAAFICLI SIVLSYIRIF STVLRIPSAE GRTKVFSTCL PHLFVATFFL SAAGFEFLRL PSDSSSTVDL VFSVFYTVIP PTLNPVIYSL RNDSMKAALR 310 320 330 KMLSKEELPQ RKMCLKAMFK L
Transmembrane Helices:
TMR7 TMR6 TMR5 TMR4 TMR3 TMR2 TMR1 D V T S L I F E Y N I S I Y G L S L K R E F V L R L F E I E N A A H M Q V L N A I L I Q Y F V S F G A A A L A L G S Q L I C S Q P V V L A H I V T A S L F T T F L G G A F F V T V S V L F L T P P F T A F A A S I W V L A I F I F C L L L Y T V P N V F L H L C I A I V A S S A D L L T L A S Y I P L C V I S I H R C I A V E S L H K L L N G T S F V Y S L A R P D V T L L F Y T I I K T R F I R I D Y S M Y M P S V T I I G E A S V T S A Y R D I R L Q C I A UniProt | I-TASSER | AlphaFold | HORDE | GeneCards
| Odorant | EC50 | Adjusted Top | Antagonist? | Aroma Notes |
|---|---|---|---|---|
| patchoulol | -5.66 1 | 10 1 | patchouli, earthy, camphorous, powdery | |
| 2-(tricyclopropylsilyl)-propan-2-ol | -4.92 2 | - | woody, patchouli, resinous, earthy | |
| geosmin | -3.79 2 | 1 2 | earthy, fresh, musty, soil | |
| (Z)-3-hexen-1-ol | -3 3 | (agonist) 3 | fresh, green, grassy, foliage, vegetable, herbal, oily, melon_rind, pungent, lettuce |
1.) Roger EmterAndreas Natsch Modified olfactory receptors WO2024126820A1
2.) Roger Emter, Christel Merillat, Fiona Buchli, Felix Flachsmann, Andreas Natsch. Decoding human olfaction by high heterologous expression of odorant receptors detecting signature odorants. Current Biology, October 10, 2025
3.) Mainland JD, Li YR, Zhou T, Liu WL, Matsunami H. Human olfactory receptor responses to odorants. Sci Data. 2015 Feb 3;2:150002. doi: 10.1038/sdata.2015.2. PMID: 25977809; PMCID: PMC4412152.
| Prot. | Sim. | Expr. | 2.53 | 3.29 | 3.32 | 3.33 | 3.36 | 3.37 | 3.40 | 3.41 | 4.53 | 4.56 | 4.57 | 4.60 | 45.49 | 45.51 | 45.52 | 45.53 | 5.39 | 5.42 | 5.43 | 5.46 | 5.47 | 6.48 | 6.51 | 6.55 | 6.59 | 7.38 | 7.39 | 7.41 | 7.42 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| OR14J1 | 100 | 88% | F | V | F | I | A | S | V | A | G | S | G | H | F | D | V | P | L | F | T | A | A | L | A | F | P | S | V | Y | T |
| OR14L1 | 91 | Y | A | F | M | A | T | V | A | G | C | G | H | F | N | I | P | V | F | G | L | V | M | G | Y | I | S | A | Y | T | |
| OR14A16 | 87 | 100% | L | V | L | L | A | S | L | L | G | I | A | H | F | D | I | P | L | I | N | L | D | L | G | Y | A | S | V | Y | T |
| OR5J2 | 84 | 57% | Y | H | F | G | I | T | G | F | G | N | T | H | F | D | I | P | L | F | S | I | A | Y | L | Y | S | S | M | Y | T |
| OR2G6 | 84 | 100% | F | L | A | M | G | S | C | I | G | T | S | Q | F | E | V | P | L | A | S | F | L | Y | I | Y | A | S | L | Y | T |
| OR2J1 | 84 | Y | L | V | L | G | T | C | V | G | T | S | H | F | E | V | P | L | M | S | F | V | F | V | Y | P | A | L | Y | T | |
| OR14C36 | 84 | 84% | Y | V | V | V | V | Y | L | L | G | Y | A | H | F | D | I | P | I | S | A | V | G | L | C | Y | P | S | G | Y | S |
| OR5C1 | 83 | 100% | Y | M | F | A | A | D | C | C | G | S | A | H | F | D | I | P | L | I | C | I | Q | Y | L | Y | S | S | V | Y | T |
| OR5H2 | 83 | 65% | I | F | F | A | G | T | C | F | G | H | A | H | Y | D | I | I | V | L | S | I | Q | Y | L | Y | A | S | V | Y | T |
| OR10P1 | 83 | 80% | Y | M | F | I | G | I | C | C | G | T | A | H | L | D | I | L | V | A | T | F | I | F | A | Y | Q | S | L | Y | T |
| OR5AR1 | 82 | 53% | Y | F | F | V | V | D | C | Y | G | S | L | H | F | E | I | P | L | L | C | I | E | Y | V | Y | T | S | V | Y | T |
| OR1J1 | 82 | 100% | F | T | F | I | A | D | S | F | A | C | A | H | F | D | L | G | I | A | A | A | I | Y | I | Y | P | S | V | Y | T |
| OR11L1 | 82 | 100% | Y | L | F | V | G | A | C | F | G | T | G | P | F | D | L | P | I | L | S | V | L | Y | M | Y | S | S | V | Y | T |
| OR2J3 | 82 | 100% | Y | L | V | L | G | T | C | V | G | N | S | H | F | E | V | P | L | T | S | F | V | F | A | Y | P | A | L | Y | T |
| OR5AP2 | 82 | 61% | Y | F | F | G | L | G | C | F | G | N | A | H | Y | D | T | P | I | F | S | I | V | F | I | Y | T | S | V | Y | T |
| OR14I1 | 82 | 80% | Y | V | F | S | A | S | L | A | C | Y | A | H | F | D | I | P | T | L | S | L | V | L | G | A | I | A | L | Y | T |
| OR2B8 | 81 | Y | L | S | L | G | S | C | V | G | N | S | Q | L | E | V | P | L | V | S | I | L | Y | A | Y | G | S | L | Y | T | |
| OR2G3 | 81 | 80% | F | L | S | L | G | S | C | I | G | S | S | H | I | E | V | P | L | V | S | F | V | Y | I | Y | S | S | L | Y | T |
| OR5H14 | 81 | 92% | L | L | F | A | V | T | C | F | G | H | A | H | Y | D | I | I | V | F | A | I | Q | Y | L | Y | A | S | L | Y | T |
| OR2Y1 | 81 | 73% | F | L | Y | L | G | S | C | V | G | N | S | Q | F | E | M | P | M | A | R | V | V | Y | A | Y | I | A | L | Y | T |
| OR5B21 | 81 | 100% | Y | F | F | V | A | T | C | Y | G | N | A | H | F | D | I | P | V | V | A | N | V | Y | I | Y | N | S | V | Y | T |
| OR1A1 | 81 | 73% | F | M | M | I | G | N | S | Y | G | N | A | H | Y | D | I | T | M | L | G | I | F | Y | V | Y | L | T | V | Y | T |
| OR8D1 | 81 | 96% | Y | L | F | V | V | V | G | Y | G | S | A | H | F | D | V | L | L | I | A | N | T | F | I | Y | P | S | V | Y | T |
| OR10J5 | 81 | 84% | Y | M | F | V | A | T | C | F | G | M | A | H | F | D | I | Y | N | V | S | V | I | C | A | Y | K | S | V | Y | T |
| OR2B3 | 80 | 42% | Y | L | F | L | G | A | C | L | G | N | S | Q | F | E | V | P | L | F | S | I | L | Y | A | Y | P | S | L | Y | G |
| OR5B2 | 80 | 100% | Y | M | F | V | A | T | N | Y | G | N | A | H | F | D | V | P | L | M | S | N | I | Y | V | Y | S | S | V | Y | A |
| OR5P2 | 80 | 100% | Y | L | A | A | A | T | C | V | G | I | A | Y | F | D | F | A | L | S | S | I | I | Y | I | Y | N | S | V | Y | T |
| OR2B2 | 80 | Y | L | F | L | G | S | C | L | G | N | S | Q | F | E | V | P | L | I | S | F | L | Y | A | Y | P | S | L | C | G | |
| OR2T4 | 80 | 80% | Y | M | Y | V | A | G | F | F | G | D | G | F | F | E | V | P | M | C | C | M | L | Y | A | Y | S | S | V | Y | T |
| OR5V1 | 80 | 96% | Y | L | F | V | V | G | C | L | G | N | S | H | F | D | I | P | L | T | G | I | G | Y | A | Y | I | S | V | Y | S |
| OR11G2 | 80 | 80% | Y | F | F | F | G | S | C | F | G | W | F | P | L | D | P | A | F | L | S | P | V | Y | V | Y | P | T | L | Y | S |