☰

Olfactory Receptor family 4 subfamily K member 2.

Estimated Expression: 100% of the population.

Expression estimate based on data from Verbeurgt et al (2014).

Sequence:

        10         20         30         40         50         60         70         80         90        100 
MDVGNKSTMS EFVLLGLSNS WELQMFFFMV FSLLYVATMV GNSLIVITVI VDPHLHSPMY FLLTNLSIID MSLASFATPK MITDYLTGHK TISFDGCLTQ 

       110        120        130        140        150        160        170        180        190        200 
IFFLHLFTGT EIILLMAMSF DRYIAICKPL HYASVISPQV CVALVVASWI MGVMHSMSQV IFALTLPFCG PYEVDSFFCD LPVVFQLACV DTYVLGLFMI 

       210        220        230        240        250        260        270        280        290        300 
STSGIIALSC FIVLFNSYVI VLVTVKHHSS RGSSKALSTC TAHFIVVFLF FGPCIFIYMW PLSSFLTDKI LSVFYTIFTP TLNPIIYTLR NQEVKIAMRK 

       310        320 
LKNRFLNFNK AMPS

Transmembrane Helices:

  TMR7     TMR6     TMR5     TMR4     TMR3     TMR2     TMR1   


L I K D       S   V Y T D     A F   S I T K      L Y  L E W S  
 F V S   S L P W   L G L   I V Q S   G D F    D T I    F M Q   
F I T Y   M Y I   S I M F   M S H   Q T L C  M K P T  V M F F  
 T P T   F I C P   G S T   M V G M   F F I    A F S    L S F   
I P N L   G F F   L A I I   I W S   F L H L  A L S M  A V Y L  
 T Y I   L F V V   F C S   A V V L   T G T    D I I    V M T   
          I F H   F L V I   A V C   L I I E  S L N T  L S N G  
         A T C T   Y S N   V Q P S   A M L    L L F    I V I   
          S L A   L V I V           D F S M  Y M P S  V I V T  
         K S S G   V T V             I Y R                 D   
                      H K           K C I A                    
    

    UniProt | I-TASSER | AlphaFold | HORDE | GeneCards | ORDB
Odorant EC50 Adjusted Top Antagonist? Aroma Notes
eugenol -5.71 1 0.8147 1  clove, spicy, sweet, woody
exaltolide - 2.8846 2  animal, fruity, musk, natural, powdery
benzaldehyde - 1.9231 2  sharp, sweet, bitter, almond, cherry
hydrocinnamaldehyde - 1.9231 2  fresh, cortex, green, leafy, foliage, balsamic, storax, aldehydic, floral, melon
isobutyraldehyde - 1.9231 2  cereal, malty
muscone - 1.3462 2  musk, animal, powdery
2-heptanone -1.62 1 0.0324 1  banana, cheesy, coconut, creamy, fruity, green, herbal, ketonic, spicy, sweet, waxy, woody
civetone - 0.5769 2  clean, musk, dry, animal, sweet
globanone - 0.4808 2  animal, balsamic, cloth, dry, floral, laundered, musk, tobacco, waxy
habanolide - 0 2  animal, cloth, dry, laundered, metallic, musk, powdery, sweet, tropical, waxy

1.) Mainland JD, Li YR, Zhou T, Liu WL, Matsunami H. Human olfactory receptor responses to odorants. Sci Data. 2015 Feb 3;2:150002. doi: 10.1038/sdata.2015.2. PMID: 25977809; PMCID: PMC4412152.

2.) Ashti Baghaei, K. (2015). Large scale analysis of olfactory receptors with highly genetically variations in relation with specific anosmia (Doctoral dissertation, Bochum, Ruhr-Universität Bochum, Diss., 2013).
Prot.Sim.Expr.2.53 3.29 3.32 3.33 3.36 3.37 3.40 3.41 4.53 4.56 4.57 4.60 45.49 45.51 45.52 45.53 5.39 5.42 5.43 5.46 5.47 6.48 6.51 6.55 6.59 7.38 7.39 7.41 7.42
OR4K2100 100%L I L H T G I I G H S Q F D L P M T S I A F C Y P S V Y T
OR4K392L M L H G G I V G H A Q F D L P M T S I A F C Y P S V Y T
OR4D191 100%Y I F H G G V F G H S Q Y D V P M N S L V F C Y P S I Y T
OR4K1491 80%L I L H G G M V G H S Q F D L P M D S L S F C Y P S V Y T
OR4K1391 96%L M M H G G M M G H S Q F D L P V D S L S F C Y P S V Y T
OR4K1591 42%V I V H T G M V G H T Q F D L P I D S L S F C Y P A V Y T
OR4Q389 92%L I L H G A M F G H S Q Y D V P V N S L S F C Y F S L Y T
OR4K1788 84%L I L H G G M V G H S Q F D L P I N S I S F C Y P A V Y T
OR4Q288Y L L H G A M F G H S Q F D V P M N S I S F C Y F S V Y N
OR4D588 80%Y L F H G G I F G H S Q Y D V P M N N V T F C Y P S V Y T
OR4D1188 34%F I F H G G I F G H S Q Y D V P M N N V T F C Y P S V F T
OR4F488 92%L I L H G G M V G H S Q Y D L P V N S L T F C Y P A V Y S
OR4F588 92%L I L H G G M V G H S Q Y D L P V N S L T F C Y P A V Y S
OR4F1788 92%L I L H G G M V G H S Q Y D L P V N S L T F C Y P A V Y S
OR4D987 100%F M F H G G V F G H S Q Y D V P M N N V S F C Y P S V F T
OR4N287 73%Y L L H G G G L G H S Q F D V P M N S M T F G Y P S L H T
OR4E286 96%H L L H A C I F G H S Q F D V P I N S I S F C Y P S V Y T
OR4N585 96%Y L L H G A M F G H S Q F D V P M N S L S F A Y F S L H T
OR4D684 65%F I F H G G I F G H S Q Y Y V L M N N V T F C Y P S I N T
OR4L184 11%L M M H G G M T G H S Q F D L P V D S L S F C Y P A V Y T
OR4K584 61%Q I I H T G M V S H T Q F D L P I N S L S F C Y P A I Y T
OR4D1084 96%F M F H G G V F G H S Q Y D V H M N N L T F C Y P S V F T
OR4N484 34%Y L L H G G G L G H S Q F D V R M N S M T F A Y P S L H T
OR4C383 34%Y L A H G G I I G H S Q A D L Y V N S I C F C Y P A L Y G
OR4A4783Y L E H G G V F G H S Q F D M Y V N G A C F C Y P S V Y T
OR4M183Y L L H G A M F G H S Q F D I T M S S I S F S Y P S V H T
OR4C4583 7%A F Y Y T L I I G H G Q M D L V I N S L C F F Y P T V C T
OR4P483 57%Y L T H G G I F G H S Q F D V Y V N S I A F A Y V A L Y T
OR4M283 92%Y L L H G A M F G H S Q F D I T M S S I S F S Y P S V N T
OR4A1582 15%Y L D H A G V I G H S Q L D L Y M N G I C F C Y P T V L T
OR4C1382 7%Y V E H R G V I G H A Q M D L Y I N S I C F C Y P A V Y T
OR4A1682Y L E H G G V F G H S Q V D M Y V N G I C F C Y P T V Y S
OR4D282 96%F I F H G G V F G H S Q Y D V P K N S L D F S Y P S I H T
OR4K182Q I L H V G M M G H S H F D L P T N S I S F C Y P S V Y T
OR4C581S L E H G G I I G H A Q I D L F V N S M C F C Y P S V Y T
OR4S281 57%Y L V H G C I F G H S Q F D V H V N S I A F C Y D A V Y T
OR4A581 15%Y L D H G G V F G H S Q S D M H V N S I C F C Y P T V Y T
OR4F381 100%A I I H G G M V G H S Q Y D L P V N S I C F P Y P A I D A
OR4F2181 100%A I I H G G M V G H S Q Y D L P V N S I C F P Y P A I D A
OR10G881 57%F L F H G G C F G H S Q L D A P I T V V A F G Y G A V Y T
OR4B180 69%Y I F H G V I L G H S Q F D L Q V N S F S F A Y P A V Y T
OR4F680F I I H G G M V G H S Q F D L P V N S I S F L Y P A I D A
OR4C1580 69%F L E H A G V I G H S Q M D L Y V N S I C F C Y P A I Y I
×
 
 

Code version:
 

Docker used:
 

Files:
Active model: text 3D download
Inactive model: text 3D download
Active dock: text 3D download
Inactive dock: text 3D download
JSON entry: text   download