Olfactory Receptor family 4 subfamily K member 2.
Estimated Expression: 100% of the population.
Expression estimate based on data from Verbeurgt et al (2014).
Sequence:
10 20 30 40 50 60 70 80 90 100 MDVGNKSTMS EFVLLGLSNS WELQMFFFMV FSLLYVATMV GNSLIVITVI VDPHLHSPMY FLLTNLSIID MSLASFATPK MITDYLTGHK TISFDGCLTQ 110 120 130 140 150 160 170 180 190 200 IFFLHLFTGT EIILLMAMSF DRYIAICKPL HYASVISPQV CVALVVASWI MGVMHSMSQV IFALTLPFCG PYEVDSFFCD LPVVFQLACV DTYVLGLFMI 210 220 230 240 250 260 270 280 290 300 STSGIIALSC FIVLFNSYVI VLVTVKHHSS RGSSKALSTC TAHFIVVFLF FGPCIFIYMW PLSSFLTDKI LSVFYTIFTP TLNPIIYTLR NQEVKIAMRK 310 320 LKNRFLNFNK AMPS
Transmembrane Helices:
TMR7 TMR6 TMR5 TMR4 TMR3 TMR2 TMR1 I K D T S V Y T D A F I T K H L Y L E W S V S L L P W M L G L I V Q S D F S D T I F M Q I T Y F Y I F S I M F M S H T L C G M K P T V M F F P T F I C P G G S T M V G M F I Q A F S L S F P N L T F F L L A I I I W S L H L F A L S M A V Y L Y I I F V V I F C S A V V L G T F D I I V M T F H A F L V I A V C I I E T S L N T L S N G T C T S Y S N V Q P S M L L L L F I V I L A K L V I V F S M A Y M P S V I V T S S G R V T V Y R D D H K C I A I UniProt | I-TASSER | AlphaFold | HORDE | GeneCards | ORDB
| Odorant | EC50 | Adjusted Top | Antagonist? | Docks | Aroma Notes |
|---|---|---|---|---|---|
| eugenol | -5.71 1 | 0.8147 1 | clove, spicy, sweet, woody | ||
| exaltolide | - | 2.8846 2 | animal, fruity, musk, natural, powdery | ||
| benzaldehyde | - | 1.9231 2 | sharp, sweet, bitter, almond, cherry | ||
| hydrocinnamaldehyde | - | 1.9231 2 | fresh, cortex, green, leafy, foliage, balsamic, storax, aldehydic, floral, melon | ||
| isobutyraldehyde | - | 1.9231 2 | cereal, malty | ||
| muscone | - | 1.3462 2 | musk, animal, powdery | ||
| 2-heptanone | -1.62 1 | 0.0324 1 | banana, cheesy, coconut, creamy, fruity, green, herbal, ketonic, spicy, sweet, waxy, woody | ||
| civetone | - | 0.5769 2 | clean, musk, dry, animal, sweet | ||
| globanone | - | 0.4808 2 | animal, balsamic, cloth, dry, floral, laundered, musk, tobacco, waxy | ||
| habanolide | - | 0 2 | animal, cloth, dry, laundered, metallic, musk, powdery, sweet, tropical, waxy |
1.) Mainland JD, Li YR, Zhou T, Liu WL, Matsunami H. Human olfactory receptor responses to odorants. Sci Data. 2015 Feb 3;2:150002. doi: 10.1038/sdata.2015.2. PMID: 25977809; PMCID: PMC4412152.
2.) Ashti Baghaei, K. (2015). Large scale analysis of olfactory receptors with highly genetically variations in relation with specific anosmia (Doctoral dissertation, Bochum, Ruhr-Universität Bochum, Diss., 2013).