Olfactory Receptor family 4 subfamily D member 11.
Sequence:
10 20 30 40 50 60 70 80 90 100 MELGNVTRVK EFIFLGLTQS QDQSLVLFLF LCLVYMTTLL GNLLIMVTVT CESRLHTPMY FLLRNLAILD ICFSSTTAPK VLLDLLSKKK TISYTSCMTQ 110 120 130 140 150 160 170 180 190 200 IFLFHLLGGA DIFSLSVMAF DCYMAISKPL HYVTIMSRGQ CTALISASWM GGFVHSIVQI SLLLPLPFCG PNVLDTFYCD VPQVLKLTCT DTFALEFLMI 210 220 230 240 250 260 270 280 290 300 SNNGLVTTLW FIFLLVSYTV ILMTLRSQAG GGRRKAISTC TSHITVVTLH FVPCIYVYAR PFTALPTEKA ISVTFTVISP LLNPLIYTLR NQEMKSAMRR 310 320 LKRRLVPSER E
Transmembrane Helices:
TMR1 TMR2 TMR3 TMR4 TMR5 TMR6 TMR7 Q D Q S L S T Y S L L A F T D R T P L A V L S D L L T M C S I Q V F E L A Y V Y A K E F L F L V K P A L F I Q I S H S I M L I C P T V S I L C L T T S L H F V F G G G N N V F H L V T F T M Y V S F C I A G G L M W S T T V L T V V L P S I L L T D L I F I D A S I L F W L T I H S P N L L L N G A L N R V S L S A T C L L F I T C T Y I L V M I L L F F A M Q G R S Y S V S I A K T V T Y M P T M Y C D L I V T R R G S I A L T M G G A Q K S R UniProt | I-TASSER | AlphaFold | HORDE | GeneCards
| Odorant | EC50 | Adjusted Top | Antagonist? | Aroma Notes |
|---|---|---|---|---|
| 2-ethyl-1-hexanol | - | 10 1 | citrus, fresh, floral, oily, sweet, fatty, fruity | |
| beta-ionone | -3.1 2 | 2.1053 2 | beeswax, berry, floral, fruity, sweet, tropical, woody, fragrant, sour, acid, vinegar, sharp, pungent | |
| 2-ethyl-1-butanol | - | 1.5 1 | sweet, musty, alcoholic | |
| hexanal | - | 1.5 1 | aldehydic, fatty, fresh, fruity, grass, green, leafy, sweaty | |
| 2-ethyl hexanal | - | 0 1 | ||
| 2-ethyl hexanoic acid | - | 0 1 | ||
| heptanal | - | 0 1 | aldehydic, cognac, fatty, fresh, green, herbal, ozone |
1.) Cho, S.W., Ko, H.J. & Park, T.H. Identification of a Lung Cancer Biomarker Using a Cancer Cell Line and Screening of Olfactory Receptors for Biomarker Detection. Biotechnol Bioproc E 26, 55–62 (2021).
2.) S.R. Jaeger, J.F. McRae, C.M. Bava, M.K. Beresford, D. Hunter, Y. Jia, S.L. Chheang, D. Jin, M. Peng, J.C. Gamble et al, A Mendelian Trait for Olfactory Sensitivity Affects Odor Experience and Food Selection, Curr. Biol. 23 (2013) 1601-1605.