☰

Olfactory Receptor family 4 subfamily P member 4.

Estimated Expression: 57% of the population.

Expression estimate based on data from Verbeurgt et al (2014).

Sequence:

        10         20         30         40         50         60         70         80         90        100 
MEKSNNSTLF ILLGFSQNKN IEVLCFVLFL FCYIAIWMGN LLIMISITCT QLIHQPMYFF LNYLSLSDLC YTSTVTPKLM VDLLAERKTI SYNNCMIQLF 

       110        120        130        140        150        160        170        180        190        200 
TTHFFGGIEI FILTGMAYDR YVAICKPLHY TIIMSRQKCN TIIIVCCTGG FIHSASQFLL TIFVPFCGPN EIDHYFCDVY PLLKLACSNI HMIGLLVIAN 

       210        220        230        240        250        260        270        280        290        300 
SGLIALVTFV VLLLSYVFIL YTIRAYSAER RSKALATCSS HVIVVVLFFA PALFIYIRPV TTFSEDKVFA LFYTIIAPMF NPLIYTLRNT EMKNAMRKVW 

       310        320 
CCQILLKRNQ LF

Transmembrane Helices:

  TMR7     TMR6     TMR5     TMR4     TMR3     TMR2     TMR1   


F V K D       T   M H I N     T L   S I T K      L L  I N K N  
 F L A   T V P R   L G I   L F Q S   N N Y    D V M    L V E   
I I T Y   I Y I   A I V L   A S H   Q I M C  L K P T  L V F C  
 M P A   F L A P   G S N   I F G G   T F L    V T S    F L F   
L P N F   A F F   L A I L   T C C   F F H T  T Y C L  A I Y C  
 T Y I   L V V V   F T V   V I I I   I G G    D S L    M W I   
          I V H   L L V V   T N C   I F I E  S L Y N  L L N G  
         S S C T   Y S L   K Q R S   G T L    L F F    I M I   
          A L A   L I F V           D Y A M  Y M P Q  C T I S  
         K S R R   I T Y             V Y R                 T   
                      A R           K C I A                    
    

    UniProt | I-TASSER | AlphaFold | HORDE | GeneCards | ORDB
Odorant EC50 Adjusted Top Antagonist? Aroma Notes
habanolide - 6.1538 1  animal, cloth, dry, laundered, metallic, musk, powdery, sweet, tropical, waxy
caproic acid - 1.9231 1  cheesy, fatty, sour, sweaty
civetone - 0.1923 1  clean, musk, dry, animal, sweet
exaltolide - 0.1923 1  animal, fruity, musk, natural, powdery
globanone - 0 1  animal, balsamic, cloth, dry, floral, laundered, musk, tobacco, waxy
heptanal - 0 2  aldehydic, cognac, fatty, fresh, green, herbal, ozone
muscone - 0 1  musk, animal, powdery

1.) Ashti Baghaei, K. (2015). Large scale analysis of olfactory receptors with highly genetically variations in relation with specific anosmia (Doctoral dissertation, Bochum, Ruhr-Universität Bochum, Diss., 2013).

2.) Lim J. H., J. Park, E. H. Oh, H. J. Ko, S. Hong, and Park, T. H. (2014) Nanovesicle-based bioelectronic nose for the diagnosis of lung cancer from human blood. Adv. Healthcare Mater., 3: 360–366.

Prot.Sim.Expr.2.53 3.29 3.32 3.33 3.36 3.37 3.40 3.41 4.53 4.56 4.57 4.60 45.49 45.51 45.52 45.53 5.39 5.42 5.43 5.46 5.47 6.48 6.51 6.55 6.59 7.38 7.39 7.41 7.42
OR4P4100 57%Y L T H G G I F G H S Q F D V Y V N S I A F A Y V A L Y T
OR4C1588 69%F L E H A G V I G H S Q M D L Y V N S I C F C Y P A I Y I
OR4D188 100%Y I F H G G V F G H S Q Y D V P M N S L V F C Y P S I Y T
OR4B188 69%Y I F H G V I L G H S Q F D L Q V N S F S F A Y P A V Y T
OR4S288 57%Y L V H G C I F G H S Q F D V H V N S I A F C Y D A V Y T
OR4A4787Y L E H G G V F G H S Q F D M Y V N G A C F C Y P S V Y T
OR4C1687 19%L V S H G C I F S H S Q F D L Q L N S I C F C Y L A V Y T
OR10G887 57%F L F H G G C F G H S Q L D A P I T V V A F G Y G A V Y T
OR4C4687 26%Y V E H G G G I G H A Q M D L N I N S I C F C Y P A I Y T
OR4F1587 92%F I S H G G M V G H S Q Y D L P V N S I S F L Y P A I D A
OR4C387 34%Y L A H G G I I G H S Q A D L Y V N S I C F C Y P A L Y G
OR4K1787 84%L I L H G G M V G H S Q F D L P I N S I S F C Y P A V Y T
OR4A1686Y L E H G G V F G H S Q V D M Y V N G I C F C Y P T V Y S
OR4C686 69%F L E H G G I I G H A Q I D L F V N S M C F C Y P A V D S
OR4A586 15%Y L D H G G V F G H S Q S D M H V N S I C F C Y P T V Y T
OR4F486 92%L I L H G G M V G H S Q Y D L P V N S L T F C Y P A V Y S
OR4F586 92%L I L H G G M V G H S Q Y D L P V N S L T F C Y P A V Y S
OR4F1786 92%L I L H G G M V G H S Q Y D L P V N S L T F C Y P A V Y S
OR4C1286 23%Y A E H G A I I G H A Q M D L Y V N S I C F C Y S A V Y T
OR4C1385 7%Y V E H R G V I G H A Q M D L Y I N S I C F C Y P A V Y T
OR4N585 96%Y L L H G A M F G H S Q F D V P M N S L S F A Y F S L H T
OR10G785 80%F L F H G S C F G H S Q F D A P I N I V A F G Y G A V Y T
OR4D585 80%Y L F H G G I F G H S Q Y D V P M N N V T F C Y P S V Y T
OR4N285 73%Y L L H G G G L G H S Q F D V P M N S M T F G Y P S L H T
OR4F384 100%A I I H G G M V G H S Q Y D L P V N S I C F P Y P A I D A
OR4F2184 100%A I I H G G M V G H S Q Y D L P V N S I C F P Y P A I D A
OR4Q284Y L L H G A M F G H S Q F D V P M N S I S F C Y F S V Y N
OR4A1584 15%Y L D H A G V I G H S Q L D L Y M N G I C F C Y P T V L T
OR2C384 92%F F S H G A C V G T S G F E M P M A S F V Y I Y A A L Y T
OR4D1184 34%F I F H G G I F G H S Q Y D V P M N N V T F C Y P S V F T
OR4D984 100%F M F H G G V F G H S Q Y D V P M N N V S F C Y P S V F T
OR4F684F I I H G G M V G H S Q F D L P V N S I S F L Y P A I D A
OR4X184 23%Y M L H G G A F G H S Q F D V H I N G I S F C Y C A V Y T
OR4L183 11%L M M H G G M T G H S Q F D L P V D S L S F C Y P A V Y T
OR4C583S L E H G G I I G H A Q I D L F V N S M C F C Y P S V Y T
OR4D1083 96%F M F H G G V F G H S Q Y D V H M N N L T F C Y P S V F T
OR4Q383 92%L I L H G A M F G H S Q Y D V P V N S L S F C Y F S L Y T
OR4K283 100%L I L H T G I I G H S Q F D L P M T S I A F C Y P S V Y T
OR4K383L M L H G G I V G H A Q F D L P M T S I A F C Y P S V Y T
OR10G483 88%F L F H G S C F G H S Q F D A P I D I V A F C Y G A I Y T
OR4N482 34%Y L L H G G G L G H S Q F D V R M N S M T F A Y P S L H T
OR4E282 96%H L L H A C I F G H S Q F D V P I N S I S F C Y P S V Y T
OR4K1382 96%L M M H G G M M G H S Q F D L P V D S L S F C Y P S V Y T
OR4K1482 80%L I L H G G M V G H S Q F D L P M D S L S F C Y P S V Y T
OR4K1582 42%V I V H T G M V G H T Q F D L P I D S L S F C Y P A V Y T
OR10G982 46%F L F H G S C F G H S Q L D A P I D I V A F C Y G A I Y T
OR4M181Y L L H G A M F G H S Q F D I T M S S I S F S Y P S V H T
OR4S181 42%Y L A H G G I F G H S Q F D V H V N S I S L P Y S I L N I
OR4C1181 69%F V L H G C I F S H S Q C D L Q L N S I C F C Y P A V Y T
OR4D681 65%F I F H G G I F G H S Q Y Y V L M N N V T F C Y P S I N T
OR4M281 92%Y L L H G A M F G H S Q F D I T M S S I S F S Y P S V N T
OR2G281 38%F L S H G S C V G T T Q I E V P L A S F L Y I Y A S L Y T
OR4X281 53%Y L L H G G I F G H S Q F D L V I N G L S F C S S A V Y T
×
 
 

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