Olfactory Receptor family 8 subfamily B member 2.
Sequence:
10 20 30 40 50 60 70 80 90 100 MLARNNSLVT EFILAGLTDH PEFRQPLFFL FLVIYIVTMV GNLGLITLFG LNSHLHTPMY YFLFNLSFID LCYSSVFTPK MLMNFVSKKN IISNVGCMTR 110 120 130 140 150 160 170 180 190 200 LFFFLFFVIS ECYMLTSMAY DRYVAICNPL LYKVTMSHQV CSMLTFAAYI MGLAGATAHT GCMLRLTFCS ANIINHYLCD ILPLLQLSCT STYVNEVVVL 210 220 230 240 250 260 270 280 290 300 IVVGTNITVP SCTILISYVF IVTSILHIKS TQGRSKAFST CSSHVIALSL FFGSAAFMYI KYSSGSMEQG KVSSVFYTNV VPMLNPLIYS LRNKDVKVAL 310 320 RKALIKIQRR NIF
Transmembrane Helices:
TMR1 TMR2 TMR3 TMR4 TMR5 TMR6 TMR7 F E P H F G V N S M C V Y T S M F Q E M S P Q R N M L T M C G T H A V E N A A S V K G L F F L M K P T F F L R T A G I L V V G F F L F V S S V L F F V S F L F A L G M G V V S L A N T Y V I Y I S Y C L S I V F I Y A T I N T I V H S M P V V V M T D I F Y C E A F T L S P V S C T P N L G L N G S L N F S T L M M S C L I T C S F A K S Y I L T I L L F Y Y A M V Q H S Y S I S R G G F L Y M P T V Y R D V I F V Q T S K C I A I S T N H L UniProt | I-TASSER | AlphaFold | HORDE | GeneCards | ORDB
Odorant | EC50 | Adjusted Top | Antagonist? | Aroma Notes |
---|---|---|---|---|
4-chromanone | -4.9 1 | 8.4211 1 | ||
androstenone | -4.74 2 | 1.0966 2 | animal, musky |
1.) Xiaojing Cong, Wenwen Ren, Jody Pacalon, Claire A. de March, Lun Xu, Hiroaki Matsunami, Yiqun Yu, Jérôme Golebiowski Functions of olfactory receptors are decoded from their sequence https://doi.org/10.1101/2020.01.06.895540
2.) Mainland JD, Li YR, Zhou T, Liu WL, Matsunami H. Human olfactory receptor responses to odorants. Sci Data. 2015 Feb 3;2:150002. doi: 10.1038/sdata.2015.2. PMID: 25977809; PMCID: PMC4412152.