Olfactory Receptor family 8 subfamily B member 3.
Sequence:
10 20 30 40 50 60 70 80 90 100 MLARNNSLVT EFILAGLTDH PEFQQPLFFL FLVVYIVTMV GNLGLIILFG LNSHLHTPMY YFLFNLSFID LCYSSVFTPK MLMNFVSKKN IISYVGCMTQ 110 120 130 140 150 160 170 180 190 200 LFFFLFFVIS ECYMLTSMAY DRYVAICNPL LYKVTMSHQV CSMLTFAAYI MGLAGATAHT GCMLRLTFCS ANIINHYLCD ILPLLQLSCT STYVNEVVVL 210 220 230 240 250 260 270 280 290 300 IVVGINIMVP SCTILISYVF IVTSILHIKS TQGRSKAFST CSSHVIALSL FFGSAAFMYI KYSSGSMEQG KVSSVFYTNV VPMLNPLIYS LRNKDVKVAL 310 320 RKALIKIQRR NIF
Transmembrane Helices:
TMR1 TMR2 TMR3 TMR4 TMR5 TMR6 TMR7 F E P H F G V Y S M C V Y T S M F Q E M S P Q Q N M L T M C G T H A V E N A A S V K G L F F L M K P T F F L Q T A G I L V V G F F L F V S S V L F F V S F L F A L G M G V V S L A N T Y V I Y V S Y C L S I V F I Y A M I N I I V H S M P V V V M T D I F Y C E A F T L S P V S C T P N L G L N G S L N F S T L M M S C L I T C S F A K S Y I L I I L L F Y Y A M V Q H S Y S I S R G G F L Y M P T V Y R D V I F V Q T S K C I A I S T N H L UniProt | I-TASSER | AlphaFold | HORDE | GeneCards | ORDB
| Odorant | EC50 | Adjusted Top | Antagonist? | Aroma Notes |
|---|---|---|---|---|
| oranger crystals | -3.8 1 | 3.5294 1 | sweet, neroli, orangeflower, powdery, honey, floral, orange, naphthyl, citrus | |
| para-anisaldehyde | -4.2 1 | 2.5882 1 | sweet, powdery, mimosa, floral, hawthorn, balsamic, vanilla, anise, woody, coumarinic, creamy, spicy | |
| (R)-(-)-carvone | -3.4 1 | 0.7647 1 | herbal, minty, spearmint, sweet | |
| hexanal | - | 0.5 2 | aldehydic, fatty, fresh, fruity, grass, green, leafy, sweaty |
1.) Ieki T, Yamanaka Y, Yoshikawa K (2022) Functional analysis of human olfactory receptors with a high basal activity using LNCaP cell line. PLOS ONE 17(4): e0267356.
2.) Ojiro I, Katsuyama H, Kaneko R, Ogasawara S, Murata T, Terada Y, et al. (2024) Enhancement of transcription efficiency by TAR-Tat system increases the functional expression of human olfactory receptors. PLoS ONE 19(6): e0306029. https://doi.org/10.1371/journal.pone.0306029