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SMILES:
CC12CCC3C(C1CC=C2)CCC4C3(CCC(=O)C4)C

Aroma Description:
animal, musky1

Receptor log10 EC50 Adj. Top Antagonist? Correlated Perceptual Qualities
OR7D4 -5.39 2, -5.92 4 1.0801 2, 10 4  animal
OR4D1 - 10 6  animal
OR8B2 -4.74 2 1.0966 2  animal
OR2J2 -5 2 0.2033 2, 0 3  tart, carnation, orange, warm, hay, clove, cinnamon, sweet
OR7C1 -4.54 2 0.1833 2  animal
OR4X2 -4.52 2 0.1983 2  grape
OR6Q1 -4.46 2 0.1408 2  (insufficient data)
OR4F17 -4.32 2 0.1822 2  clove, animal
OR5R1 -4.15 2 0.1662 2  spearmint, acacia, chemical, hawthorn, mimosa, tonka, almond, coumarinic
OR1B1 - 3.8462 7  cotton_candy, jammy, caramellic
OR10A5 -3.26 2 0.7467 2  candy, warm, cinnamon
OR10A6 -3.06 2 0.4989 2  floral, honey, rhubarb, neroli, cyclamen, cinnamyl, hyacinth, rose, dirty, balsamic
OR9G1 -2.67 2 0.0602 2  carnation, malty, candy, warm, clove, cinnamon
OR10G6 -2.42 2 0.0848 2  fusel, banana
OR1C1 - 1 3  blueberry, bois_de_rose
OR10G3 - 0 3   
OR10G7 - 0 3   
OR10J5 - 0 3   
OR11A1 - 0 3   
OR2A25 - 0 3   
OR2B11 - 0 3   
OR2J3 - 0 3   
OR51E1 - 0 3   
OR51L1 - 0 3   
OR56A4 - 0 3   
OR5K1 - 0 3   
OR8D1 - 0 3   
OR8K3 - 0 3   
VN1R1 - 0 5   
OR5I1 - 0 7   
OR1A1 - -1.4333 3   
OR2W1 - -2.3333 3   
OR5P3 - -2.6667 3   
 

SMILES:
CC12CCC3C(C1CC=C2)CCC4C3(CCC(=O)C4)C

Aroma Description:
animal, musky

Receptor Dock Score Affinity A100 Correlated Perceptual Qualities

Dock Score: This is a measure of whether the algorithm thinks the odorant is an agonist of the receptor.
Affinity: The binding affinity, in kJ/mol, of the ligand docked in the active or inactive model, whichever is greater.
A100: A measure of the degree of activation of the receptor. See Ibrahim et al (2019).

1.) The Good Scents Company

2.) Mainland JD, Li YR, Zhou T, Liu WL, Matsunami H. Human olfactory receptor responses to odorants. Sci Data. 2015 Feb 3;2:150002. doi: 10.1038/sdata.2015.2. PMID: 25977809; PMCID: PMC4412152.

3.) Adipietro KA, Mainland JD, Matsunami H (2012) Functional Evolution of Mammalian Odorant Receptors. PLoS Genet 8(7): e1002821. doi:10.1371/ journal.pgen.1002821

4.) Keller A, Zhuang H, Chi Q, Vosshall LB, Matsunami H. Genetic variation in a human odorant receptor alters odour perception. Nature. 2007 Sep 27;449(7161):468-72. doi: 10.1038/nature06162. Epub 2007 Sep 16. PMID: 17873857.

5.) I. Wallrabenstein, J. Gerber, S. Rasche, I. Croy, S. Kurtenbach, T. Hummel, H. Hatt, The smelling of Hedione results in sex-differentiated human brain activity, NeuroImage, Volume 113, 2015, Pages 365-373, ISSN 1053-8119

6.) Hartmann C, Triller A, Spehr M, Dittrich R, Hatt H, Buettner A. Sperm-Activating Odorous Substances in Human Follicular Fluid and Vaginal Secretion: Identification by Gas Chromatography–Olfactometry and Ca2 Imaging. Chempluschem 78: 695–702, 2013. doi:10.1002/cplu.201300008

7.) Ashti Baghaei, K. (2015). Large scale analysis of olfactory receptors with highly genetically variations in relation with specific anosmia (Doctoral dissertation, Bochum, Ruhr-Universität Bochum, Diss., 2013).