SMILES:
CC(=CCCC(C)(C=C)O)C

Aroma Description:
blueberry, bois_de_rose, citrus, floral, green, rose, sweet, woody1

Receptor Expression log10 EC50 Adj. Top Antagonist? Correlated Perceptual Qualities
OR1C1 100 -7.86 2, -2.79 3, -2.57 4, -2.8 8, -6.09 11, -3.69 13 1.4377 2, 10 3, (agonist) 4, 0.5294 8, (agonist) 11  blueberry, bois_de_rose, sweet, rose, citrus
OR10A6 100 -6.25 10 -  peach, sweet, coconut, floral, lactonic, cyclamen, neroli, waxy, dairy, honey
VN1R5 ? - 9 6  tart, orange_peel, aldehydic, spearmint, caraway, waxy, peely, citrus, blueberry, rose
OR13C3 92 -8.14 2 0.1149 2  (insufficient data)
OR2AG2 100 -5.25 10 -  cinnamyl, sweet, cinnamon, floral, rose, balsamic, hyacinth, honey, magnolia, citrus
VN1R3 ? - 7.3 6  orange_peel, peely, aldehydic
OR1D2 100 -4.26 7 -  rose, citrus, fresh, sweet, floral, waxy, fatty, bois_de_rose, peach, blueberry
OR51T1 76 -4.4 8 3.8235 8  spearmint, dairy, caraway, orangeflower, sharp, neroli, milky, creamy, blueberry, minty
OR1N2 100 -3.83 2 0.1061 2  sweet, rose, citrus, blueberry, bois_de_rose, floral, soapy, amber, berry
OR1A1 73 -3.4 8 -1.1667 4, 0.7059 8  sweet, citrus, fresh, rose, herbal, waxy, orange, spearmint, floral, aldehydic
OR13A1 100 -2.8 2 0.1774 2  (insufficient data)
OR2A25 100 -2.06 3 0.5833 3, 0 4  rose, peony, floral, geranium, citrus
OR2W3 100 - 0.9302 9  sweet, lemon, citrus, clove
OR7D4 96 - 0.2 5  animal, citrus, orange, peely, tart, aldehydic, blueberry
OR10G3 96 - 0 4   
OR10G7 80 - 0 4   
OR10J5 84 - 0 4   
OR11A1 100 - 0 4   
OR2B11 100 - 0 4   
OR2J2 92 - 0 4   
OR2J3 100 - 0 4   
OR2W1 53 - 0 4   
OR51E1 100 - 0 4   
OR51L1 88 - 0 4   
OR56A4 100 - 0 4   
OR5K1 100 - 0 4   
OR8D1 96 - 0 4   
OR8K3 92 - 0 4   
OR11H4 100 - 0 10   
OR7A17 100 - 0 12   
OR5P3 100 - -2.2667 4   
 

SMILES:
CC(=CCCC(C)(C=C)O)C

Aroma Description:
blueberry, bois_de_rose, citrus, floral, green, rose, sweet, woody

Receptor Expr.% Agonist? Dock Score Known agonist Correlated Perceptual Qualities

Dock Score is a measure of how strongly the algorithm thinks the odorant is likely to be an agonist of the receptor.
Receptors in italics are "orphans", i.e. receptors whose agonists have not been identified experimentally.

1.) The Good Scents Company

2.) Mainland JD, Li YR, Zhou T, Liu WL, Matsunami H. Human olfactory receptor responses to odorants. Sci Data. 2015 Feb 3;2:150002. doi: 10.1038/sdata.2015.2. PMID: 25977809; PMCID: PMC4412152.

3.) C. Trimmer, A. Keller, N. R. Murphy, L. L. Snyder, J. R. Willer, M. H. Nagai, N. Katsanis, L. B. Vosshall, H. Matsunami, and J. D. Mainland Genetic variation across the human olfactory receptor repertoire alters odor perception PNAS | May 7, 2019 | vol. 116 | no. 19 | 9475–9480

4.) Adipietro KA, Mainland JD, Matsunami H (2012) Functional Evolution of Mammalian Odorant Receptors. PLoS Genet 8(7): e1002821. doi:10.1371/ journal.pgen.1002821

5.) Keller A, Zhuang H, Chi Q, Vosshall LB, Matsunami H. Genetic variation in a human odorant receptor alters odour perception. Nature. 2007 Sep 27;449(7161):468-72. doi: 10.1038/nature06162. Epub 2007 Sep 16. PMID: 17873857.

6.) Krautwurst D. Human olfactory receptor families and their odorants. Chem Biodivers. 2008 Jun;5(6):842-52. doi: 10.1002/cbdv.200890099. PMID: 18618407.

7.) Veithen, A.; Wilin, F.; Philippeau, M.; Chatelain, P. OR1D2 is a broadly tuned human olfactory receptor. Chem. Senses 2015, 40, 262–263.

8.) Ieki T, Yamanaka Y, Yoshikawa K (2022) Functional analysis of human olfactory receptors with a high basal activity using LNCaP cell line. PLOS ONE 17(4): e0267356.

9.) Huang, J., Lam, H., Koziol-White, C., Limjunyawong, N., Kim, D., Kim, N., ... & An, S. S. (2020). The odorant receptor OR2W3 on airway smooth muscle evokes bronchodilation via a cooperative chemosensory tradeoff between TMEM16A and CFTR. Proceedings of the National Academy of Sciences, 117(45), 28485-28495.

10.) Duroux R, Mandeau A, Guiraudie-Capraz G, Quesnel Y, Loing E. A Rose Extract Protects the Skin against Stress Mediators: A Potential Role of Olfactory Receptors. Molecules. 2020 Oct 16;25(20):4743. doi: 10.3390/molecules25204743. PMID: 33081083; PMCID: PMC7587601.

11.) Dunkel, A.; Steinhaus, M.; Kotthoff, M.; Nowak, B.; Krautwurst, D.; Schieberle, P.; Hofmann, T. Nature’s chemical signatures in human olfaction: A foodborne perspective for future biotechnology. Angew. Chem. Int. Ed. Engl. 2014, 53, 7124–7143.

12.) Dan Takase, Tomohiro Shirai, Kensuke Misawa, Hiroaki Matsunami, Keiichi Yoshikawa, An odorant receptor for a key odor constituent of ambergris. Communications Biology | (2025)8:792. doi: 10.1038/s42003-025-08229-y

13.) Roger EmterAndreas Natsch Modified olfactory receptors WO2024126820A1

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