OR10G7

Olfactory Receptor family 10 subfamily G member 7.

Estimated Expression: 80% of the population.

Expression estimate based on data from Verbeurgt et al (2014).

Sequence:

        10         20         30         40         50         60         70         80         90        100 
MSNATLLTAF ILTGLPHAPG LDAPLFGIFL VVYVLTVLGN LLILLVIRVD SHLHTPMYYF LTNLSFIDMW FSTVTVPKML MTLVSPSGRT ISFHSCVAQL 

       110        120        130        140        150        160        170        180        190        200 
YFFHFLGSTE CFLYTVMSYD RYLAISYPLR YTNMMTGRSC ALLATGTWLS GSLHSAVQTI LTFHLPYCGP NQIQHYFCDA PPILKLACAD TSANEMVIFV 

       210        220        230        240        250        260        270        280        290        300 
NIGLVASGCF VLIVLSYVSI VCSILRIRTS EGRHRAFQTC ASHCIVVLCF FGPGLFIYLR PGSRDALHGV VAVFYTTLTP LFNPVVYTLR NKEVKKALLK 

       310        320 
LKNGSVFAQG E

Transmembrane Helices:

  TMR7     TMR6     TMR5     TMR4     TMR3     TMR2     TMR1   


H L A D  R L Y I  A S T D     T L   S I T R      V L  L G P A  
 V V G    F L G    M E N   I T Q V   S H F    T M L    P A D   
Y F V A  P G F F  V F I V   A S H   Q A V C  M K P V  I G F L  
 L T T    C L V    G I N   L S G S   F Y L    T V T    V L F   
F L P T  V I C H  S A V L   L W T   L F H F  S F W M  L V Y V  
 V P N    S A C    F C G   G T A L   T S G    D I F    L V T   
    Y V  T Q F A  V I L V   L A C   L F C E  S L N T  L L N G  
          R H R    Y S L   S R G T   V T Y    L F Y    L L I   
         G E S T  V I S V           D Y S M  Y M P T  V R I V  
                   I S C             L Y R                 D   
                    I R L           Y S I A                    
    

    UniProt | I-TASSER | AlphaFold | HORDE | GeneCards | ORDB

Odorant	EC₅₀	Adjusted Top	Aroma Notes
eugenol	-9 ¹	5.654 ¹	clove, spicy, sweet, woody
creosol	-6 ²	10 ²	burnt, clove, leathery, medicinal, phenolic, smoky, spicy, vanilla, woody
isoeugenol	-5.54 ¹	10 ¹	carnation, clove, floral, spicy, sweet, woody
propyl diantilis	-5.84 ¹	-	spicy, vanilla, smoky
guaiacol	-6 ³	8.1972 ³	phenolic, smoky, spicy, vanilla, woody, medicinal, savory, meaty, balsamic, sweet, burnt
propenyl guaethol	-4.66 ¹	-	sweet, vanilla, woody, tobacco, spicy, phenolic, powdery, anisic, creamy, floral
methyl eugenol	-6 ⁴	2.3333 ⁴	carnation, cinnamon, clove, fresh, spicy, sweet, warm
4-vinylguaiacol	-4.7 ⁵	1.3333 ⁵	spicy, clove, carnation, phenolic, peppery, smoky, woody, powdery
delta-damascone	-	4 ¹	fruity, sweet, rose, natural, petal, currant_bud, black_currant_bud, tobacco
vanillin	-	4 ¹	chocolate, creamy, sweet, vanilla
ethyl vanillin	-4.50 ¹	0.2333 ¹	sweet, creamy, vanilla, caramellic
eugenyl acetate	-	3 ⁴	carnation, clove, floral, fresh, malty, spicy, sweet, woody
coumarin	-	0.1667 ⁴	coumarinic, hay, sweet, tonka
octyl octanoate	-	0.1667 ⁴	coconut, oily, fruity
methyl furfuryl disulfide	-	0.1333 ⁴	sulfurous, coffee, roasted, alliaceous, meaty, liver, onion, garlic, eggy
1-octanol	-	0.1333 ⁴	aldehydic, green, mushroom, orange, rose, waxy
quinoline	-	0.0667 ⁴	earthy, medicinal, musty, rubbery, tobacco
allyl phenylacetate	-	0 ⁴	honey, fruity, rummy
androstenone	-	0 ⁴	animal, musky
l-arabinose	-	0 ⁴
butyric acid	-	0 ⁴	sharp, acetic, cheesy, buttery, fruity, dairy, creamy
(S)-(+)-carvone	-	0 ⁴	bready, caraway, minty, spicy
citral	-	0 ⁴	sharp, lemon, sweet, fresh, juicy, lemon_peel, tart, green, citrus, lime, woody, herbal
coffee difuran	-	0 ⁴	cabbage, chicken, coffee, meaty, onion, roasted, sulfurous, cocoa, earthy, fungal, mild, mushroom, nutty
dimethyl disulfide	-	0 ⁴	sulfurous, vegetable, cabbage, onion, malty, creamy
2,4-DNT	-	0 ⁴
2-ethyl fenchol	-	0 ⁴	camphorous, earthy, humus, mushroom, musty, patchouli, potato, rooty, tea
geranyl acetate	-	0 ⁴	floral, rose, lavender, green, waxy, herbal, cooling, oily, soapy, citrus, winey, rummy
helional	-	0 ⁴	cyclamen, fresh, green, hay, ozone, watery
heptanal	-	0 ⁶	aldehydic, cognac, fatty, fresh, green, herbal, ozone
2-heptanone	-	0 ⁴	banana, cheesy, coconut, creamy, fruity, green, herbal, ketonic, spicy, sweet, waxy, woody
(Z)-3-hexen-1-ol	-	0 ⁴	fresh, green, grassy, foliage, vegetable, herbal, oily, melon_rind, pungent, lettuce
isobutylamine	-	0 ⁴	cheesy, fishy
d-limonene	-	0 ⁴	citrus, orange, fresh, sweet
linalool	-	0 ⁴	blueberry, bois_de_rose, citrus, floral, green, rose, sweet, woody
lyral	-	0 ⁴	aquatic, clean, cyclamen, floral, muguet, rhubarb, watery, waxy, woody
methyl salicylate	-	0 ⁴	minty, wintergreen
nonanal	-	0 ⁴	waxy, aldehydic, rose, fresh, orris, orange_peel, fatty, peely
1-nonanol	-	0 ⁴	aldehydic, citrus, clean, dusty, fatty, floral, fresh, oily, orange, rose, sweet, tart, waxy, wet
octanethiol	-	0 ⁴	sulfurous
3-octen-2-one	-	0 ⁷	earthy, spicy, herbal, sweet, mushroom, hay, blueberry
pelargonic acid	-	0 ⁴	cheesy, dairy, dirty, waxy
propionic acid	-	0 ⁴	acidic, cheesy, pungent, vinegar
pyrazine	-	0 ⁴	pungent, sweet, corn, roasted, hazelnut, barley
sotolone	-	0 ⁴	sweet, caramellic, maple, sugar, burnt_sugar, coffee, brown_sugar, cotton_candy
terpinyl acetate	-	0 ⁴	bergamot, citrus, herbal, lavender, lime
n-amyl alcohol	-	-0.0667 ⁴	fusel, oily, sweet, balsamic, pungent, fermented, bready, yeasty, winey, solvent
amyl hexanoate	-	-0.0667 ⁴	sweet, green, fruity, estery, pineapple, apple, pear, fatty, waxy, cognac, melon
benzene	-	-0.0667 ⁴	gasoline, phenolic, solvent, cinnamon
butyl formate	-	-0.0667 ⁴	fruity, plum, rummy, brandy
beta-damascone	-	-0.0667 ⁴	berry, currant, floral, fruity, honey, plum, rose, tobacco
decanal	-	-0.0667 ⁴	sweet, aldehydic, waxy, orange_peel, citrus, floral
(1S,2R,5S)-(+)-menthol	-	-0.0667 ⁴	cooling, mentholic, minty, fresh, sweet, herbal
propanal	-	-0.0667 ⁴	alcoholic, cocoa, earthy, nutty, whisky, winey

1.) Roger Emter, Christel Merillat, Fiona Buchli, Felix Flachsmann, Andreas Natsch. Decoding human olfaction by high heterologous expression of odorant receptors detecting signature odorants. Current Biology, October 10, 2025

2.) Mainland JD, Li YR, Zhou T, Liu WL, Matsunami H. Human olfactory receptor responses to odorants. Sci Data. 2015 Feb 3;2:150002. doi: 10.1038/sdata.2015.2. PMID: 25977809; PMCID: PMC4412152.

3.) C. Trimmer, A. Keller, N. R. Murphy, L. L. Snyder, J. R. Willer, M. H. Nagai, N. Katsanis, L. B. Vosshall, H. Matsunami, and J. D. Mainland Genetic variation across the human olfactory receptor repertoire alters odor perception PNAS | May 7, 2019 | vol. 116 | no. 19 | 9475–9480

4.) Adipietro KA, Mainland JD, Matsunami H (2012) Functional Evolution of Mammalian Odorant Receptors. PLoS Genet 8(7): e1002821. doi:10.1371/ journal.pgen.1002821

5.) Aya Namba, Naoko Saito, Keiichi Yoshikawa, Ichiro Mori (2015) Search method of urine odor suppressor JP2015211667A

6.) Lim J. H., J. Park, E. H. Oh, H. J. Ko, S. Hong, and Park, T. H. (2014) Nanovesicle-based bioelectronic nose for the diagnosis of lung cancer from human blood. Adv. Healthcare Mater., 3: 360–366.

7.) Motoki Yasunaga, Eiji Takai, Shoji Hattori, Kenji Tatematsu, Shun'ichi Kuroda, Effects of 3-octen-2-one on human olfactory receptor responses to vanilla flavor, Bioscience, Biotechnology, and Biochemistry, 2022;, zbac147, https://doi.org/10.1093/bbb/zbac147

Prot.	Sim.	Expr.	2.53	3.29	3.32	3.33	3.36	3.37	3.40	3.41	4.53	4.56	4.57	4.60	45.49	45.51	45.52	45.53	5.39	5.42	5.43	5.46	5.47	6.48	6.51	6.55	6.59	7.38	7.39	7.41	7.42
OR10G7	100	80%	F	L	F	H	G	S	C	F	G	H	S	Q	F	D	A	P	I	N	I	V	A	F	G	Y	G	A	V	Y	T
OR10G4	97	88%	F	L	F	H	G	S	C	F	G	H	S	Q	F	D	A	P	I	D	I	V	A	F	C	Y	G	A	I	Y	T
OR10G9	96	46%	F	L	F	H	G	S	C	F	G	H	S	Q	L	D	A	P	I	D	I	V	A	F	C	Y	G	A	I	Y	T
OR10G8	95	57%	F	L	F	H	G	G	C	F	G	H	S	Q	L	D	A	P	I	T	V	V	A	F	G	Y	G	A	V	Y	T
OR10G6	88		I	L	F	H	G	C	C	F	G	H	S	Q	F	D	I	P	T	D	I	L	A	Y	C	Y	C	A	V	Y	T
OR10S1	87	92%	L	L	F	H	A	S	C	F	G	H	A	H	F	D	I	P	M	S	I	V	A	Y	P	Y	R	A	V	Y	T
OR4P4	85	57%	Y	L	T	H	G	G	I	F	G	H	S	Q	F	D	V	Y	V	N	S	I	A	F	A	Y	V	A	L	Y	T
OR10G2	84	80%	L	L	F	H	G	S	C	F	G	H	G	Q	I	D	I	R	T	D	V	V	A	Y	C	Y	A	A	V	Y	T
OR4D1	84	100%	Y	I	F	H	G	G	V	F	G	H	S	Q	Y	D	V	P	M	N	S	L	V	F	C	Y	P	S	I	Y	T
OR10G3	83	96%	I	L	Y	H	G	S	C	F	G	H	G	Q	F	D	I	P	T	D	I	V	V	Y	C	Y	E	A	L	P	T
OR2Y1	83	73%	F	L	Y	L	G	S	C	V	G	N	S	Q	F	E	M	P	M	A	R	V	V	Y	A	Y	I	A	L	Y	T
OR4S2	82	57%	Y	L	V	H	G	C	I	F	G	H	S	Q	F	D	V	H	V	N	S	I	A	F	C	Y	D	A	V	Y	T
OR4K17	82	84%	L	I	L	H	G	G	M	V	G	H	S	Q	F	D	L	P	I	N	S	I	S	F	C	Y	P	A	V	Y	T
OR4X1	82	23%	Y	M	L	H	G	G	A	F	G	H	S	Q	F	D	V	H	I	N	G	I	S	F	C	Y	C	A	V	Y	T
OR2B11	82	100%	Y	Y	F	H	G	C	C	I	G	N	S	Q	F	E	V	P	L	L	V	F	V	Y	A	Y	P	S	L	Y	S
OR4X2	82	53%	Y	L	L	H	G	G	I	F	G	H	S	Q	F	D	L	V	I	N	G	L	S	F	C	S	S	A	V	Y	T
OR4A47	82		Y	L	E	H	G	G	V	F	G	H	S	Q	F	D	M	Y	V	N	G	A	C	F	C	Y	P	S	V	Y	T
OR10A7	82	15%	F	M	F	F	G	S	C	F	G	V	S	Q	F	D	G	P	A	S	T	F	I	Y	A	Y	K	S	L	Y	T
OR4F4	81	92%	L	I	L	H	G	G	M	V	G	H	S	Q	Y	D	L	P	V	N	S	L	T	F	C	Y	P	A	V	Y	S
OR4F5	81	92%	L	I	L	H	G	G	M	V	G	H	S	Q	Y	D	L	P	V	N	S	L	T	F	C	Y	P	A	V	Y	S
OR4F17	81	92%	L	I	L	H	G	G	M	V	G	H	S	Q	Y	D	L	P	V	N	S	L	T	F	C	Y	P	A	V	Y	S
OR4D5	81	80%	Y	L	F	H	G	G	I	F	G	H	S	Q	Y	D	V	P	M	N	N	V	T	F	C	Y	P	S	V	Y	T
OR9Q1	81	96%	Y	F	F	T	G	S	C	Y	G	S	A	R	F	D	L	P	I	F	A	V	I	F	L	Y	N	S	V	Y	T
OR4D9	81	100%	F	M	F	H	G	G	V	F	G	H	S	Q	Y	D	V	P	M	N	N	V	S	F	C	Y	P	S	V	F	T
OR4D11	81	34%	F	I	F	H	G	G	I	F	G	H	S	Q	Y	D	V	P	M	N	N	V	T	F	C	Y	P	S	V	F	T
OR4E2	81	96%	H	L	L	H	A	C	I	F	G	H	S	Q	F	D	V	P	I	N	S	I	S	F	C	Y	P	S	V	Y	T
OR9Q2	81	100%	Y	F	F	T	A	S	C	Y	G	S	A	R	F	D	L	P	I	F	A	V	M	F	L	Y	N	S	V	Y	T
OR4B1	81	69%	Y	I	F	H	G	V	I	L	G	H	S	Q	F	D	L	Q	V	N	S	F	S	F	A	Y	P	A	V	Y	T
OR2G6	80	100%	F	L	A	M	G	S	C	I	G	T	S	Q	F	E	V	P	L	A	S	F	L	Y	I	Y	A	S	L	Y	T
OR2J3	80	100%	Y	L	V	L	G	T	C	V	G	N	S	H	F	E	V	P	L	T	S	F	V	F	A	Y	P	A	L	Y	T
OR4A16	80		Y	L	E	H	G	G	V	F	G	H	S	Q	V	D	M	Y	V	N	G	I	C	F	C	Y	P	T	V	Y	S
OR2G2	80	38%	F	L	S	H	G	S	C	V	G	T	T	Q	I	E	V	P	L	A	S	F	L	Y	I	Y	A	S	L	Y	T
OR2J1	80		Y	L	V	L	G	T	C	V	G	T	S	H	F	E	V	P	L	M	S	F	V	F	V	Y	P	A	L	Y	T
OR4N5	80	96%	Y	L	L	H	G	A	M	F	G	H	S	Q	F	D	V	P	M	N	S	L	S	F	A	Y	F	S	L	H	T
OR10D3	80		F	L	F	H	G	S	C	F	G	H	S	L	F	D	I	P	S	N	V	I	S	Y	I	Y	T	Q	I	M	N

Active model:	text	3D	download
Inactive model:	text	3D	download
Active dock:	text	3D	download
Inactive dock:	text	3D	download
JSON entry:	text		download

primaryodors.org

Olfactory Receptor family 10 subfamily G member 7.

Estimated Expression: 80% of the population.

Sequence:

Transmembrane Helices: