Olfactory Receptor family 10 subfamily G member 3.
Sequence:
10 20 30 40 50 60 70 80 90 100 MERINSTLLT AFILTGIPYP LRLRTLFFVF FFLIYILTQL GNLLILITVW ADPRLHARPM YIFLGVLSVI DMSISSIIVP RLMMNFTLGV KPIPFGGCVA 110 120 130 140 150 160 170 180 190 200 QLYFYHFLGS TQCFLYTLMA YDRYLAICQP LRYPVLMTAK LSALLVAGAW MAGSIHGALQ AILTFRLPYC GPNQVDYFFC DIPAVLRLAC ADTTVNELVT 210 220 230 240 250 260 270 280 290 300 FVDIGVVVAS CFSLILLSYI QIIQAILRIH TADGRRRAFS TCGAHVTVVT VYYVPCAFIY LRPETNSPLD GAAALVPTAI TPFLNPLIYT LRNQEVKLAL 310 320 KRMLRSPRTP SEV
Transmembrane Helices:
TMR1 TMR2 TMR3 TMR4 TMR5 TMR6 TMR7 L R L P N M M G G F P L V T T D L Y I F L P S N L T R L R P V A V C I A Q L L E N A C P A G D F V F F I I S F Y L Q A G H V F T V V Y Y V V L A A L F F S I S M F H Y I S G A G I D T V V A T P L I Y I D I V T S G L M W A A V V V T V H A F P T I L Q T S L V G F C Q G A V L F C S G C T P N L L L N G L F I L T Y L L A S L I L S S F A R T Y I L I L I Y M P R Y A M L K A T Y S L R R G L W V T L Y R D I I Q I D A T H C I A I A Q Q R L UniProt | I-TASSER | AlphaFold | HORDE | GeneCards
| Odorant | EC50 | Adjusted Top | Antagonist? | Aroma Notes |
|---|---|---|---|---|
| vanillin | -3.85 1 | 6.444 1 | chocolate, creamy, sweet, vanilla | |
| ethyl vanillin | -5.01 2 | 0.6667 3 | caramellic, creamy, sweet, vanilla | |
| eugenyl acetate | -4 1 | 0.0667 3 | carnation, clove, floral, fresh, malty, spicy, sweet, woody | |
| n-amyl acetate | -1.4 1 | 0.2041 1 | banana, fruity, solvent, sweet, apple, ethereal, pear | |
| eugenol | - | 0.1 3 | clove, spicy, sweet, woody | |
| citral | - | 0.0667 3 | citrus, lemon, sharp, sweet | |
| 2-heptanone | - | 0.0333 3 | banana, cheesy, coconut, creamy, fruity, green, herbal, ketonic, spicy, sweet, waxy, woody | |
| aldehyde C-10 | - | 0.0167 3 | aldehydic, citrus, floral, orange, peel, sweet, waxy | |
| 1-nonanol | - | 0.01 3 | aldehydic, citrus, clean, dusty, fatty, floral, fresh, oily, orange, rose, sweet, tart, waxy, wet | |
| aldehyde C-9 | - | 0 3 | aldehydic, fatty, fresh, orange, orris, peel, peely, rose, waxy | |
| amyl hexanoate | - | 0 3 | apple, estery, fatty, fruity, green, pear, pineapple, sweet | |
| androstenone | - | 0 3 | animal, musky | |
| l-arabinose | - | 0 3 | ||
| benzene | - | 0 3 | ||
| butyl formate | - | 0 3 | brandy, fruity, plum, rummy | |
| butyric acid | - | 0 3 | acetic, buttery, cheesy, fruity, sharp | |
| caramel furanone | - | 0 3 | burnt, caramellic, coffee, maple, sugar, sweet | |
| coffee difuran | - | 0 3 | cabbage, chicken, coffee, meaty, onion, roasted, sulfurous, cocoa, earthy, fungal, mild, mushroom, nutty | |
| coumarin | - | 0 3 | coumarinic, hay, sweet, tonka | |
| beta-damascone | - | 0 3 | berry, currant, floral, fruity, honey, plum, rose, tobacco | |
| dimethyl disulfide | - | 0 3 | cabbage, onion, sulfurous, vegetable | |
| 2,4-DNT | - | 0 3 | ||
| 2-ethyl fenchol | - | 0 3 | camphoraceous, earthy, humus, mushroom, musty, patchouli, potato, rooty, tea | |
| geranyl acetate | - | 0 3 | floral, green, lavender, rose, waxy | |
| helional | - | 0 3 | cyclamen, fresh, green, hay, ozone, watery | |
| cis-3-hexen-1-ol | - | 0 3 | foliage, fresh, grassy, green, herbal, oily, vegetable | |
| isobutylamine | - | 0 3 | cheesy, fishy | |
| d-limonene | - | 0 3 | citrus, fresh, orange, sweet | |
| linalool | - | 0 3 | blueberry, bois_de_rose, citrus, floral, green, rose, sweet, woody | |
| lyral | - | 0 3 | aquatic, clean, cyclamen, floral, muguet, rhubarb, watery, waxy, woody | |
| (+)-menthol | - | 0 3 | cooling, mentholic, minty | |
| methyl eugenol | - | 0 3 | carnation, cinnamon, clove, fresh, spicy, sweet, warm | |
| methyl furfuryl disulfide | - | 0 3 | alliaceous, coffee, meaty, roasted, sulfurous | |
| methyl salicylate | - | 0 3 | minty, wintergreen | |
| octanethiol | - | 0 3 | sulfurous | |
| 1-octanol | - | 0 3 | aldehydic, green, mushroom, orange, rose, waxy | |
| octyl octanoate | - | 0 3 | coconut, fruity, oily | |
| pelargonic acid | - | 0 3 | cheesy, dairy, dirty, waxy | |
| propanal | - | 0 3 | alcoholic, cocoa, earthy, nutty, whiskey, winey | |
| propionic acid | - | 0 3 | acidic, cheesy, pungent, vinegar | |
| pyrazine | - | 0 3 | pungent, sweet, corn, roasted, hazelnut, barley | |
| quinoline | - | 0 3 | earthy, medicinal, musty, rubbery, tobacco | |
| terpinyl acetate | - | 0 3 | bergamot, citrus, herbal, lavender, lime | |
| allyl phenylacetate | - | -0.0167 3 | fruity, honey, rummy | |
| pentanol | - | -0.0167 3 | balsamic, fermented, fusel, oily, sweet |
1.) Mainland JD, Li YR, Zhou T, Liu WL, Matsunami H. Human olfactory receptor responses to odorants. Sci Data. 2015 Feb 3;2:150002. doi: 10.1038/sdata.2015.2. PMID: 25977809; PMCID: PMC4412152.
2.) Dunkel, A.; Steinhaus, M.; Kotthoff, M.; Nowak, B.; Krautwurst, D.; Schieberle, P.; Hofmann, T. Nature’s chemical signatures in human olfaction: A foodborne perspective for future biotechnology. Angew. Chem. Int. Ed. Engl. 2014, 53, 7124–7143.
3.) Adipietro KA, Mainland JD, Matsunami H (2012) Functional Evolution of Mammalian Odorant Receptors. PLoS Genet 8(7): e1002821. doi:10.1371/ journal.pgen.1002821