Olfactory Receptor family 52 subfamily E member 8.
Sequence:
10 20 30 40 50 60 70 80 90 100 MAGRMSTSNH TQFHPSSFLL LGIPGLEDVH IWIGVPFFFV YLVALLGNTA LLFVIQTEQS LHEPMYYFLA MLDSIDLGLS TATIPKMLGI FWFNTKEISF 110 120 130 140 150 160 170 180 190 200 GGCLSHMFFI HFFTAMESIV LVAMAFDRYI AICKPLRYTM ILTSKIISLI AGIAVLRSLY MVVPLVFLLL RLPFCGHRII PHTYCEHMGI ARLACASIKV 210 220 230 240 250 260 270 280 290 300 NIRFGLGNIS LLLLDVILII LSYVRILYAV FCLPSWEARL KALNTCGSHI GVILAFFTPA FFSFLTHRFG HNIPQYIHII LANLYVVVPP ALNPVIYGVR 310 320 TKQIRERVLR IFLKTNH
Transmembrane Helices:
TMR1 TMR2 TMR3 TMR4 TMR5 TMR6 TMR7 D E L G I G L G G F S L V K I S T I Y Q P I H V M K P I S L C F V L P R I N L F S F I I H V G I W T A T F F M H V V M G L G F F A P L N A L F F P S L G L F H I Y L S R S I N T F F A V V Y L Y V F D I S M A T F L V A L L L L L I V A P P V L A V D L M A I S E I G A I I V D G I H S P N L T N G L L F Y A V L V L S I L I I L G C T G Y I V L L A Y M P E F A M I K S T V Y S N L A K R V Q I V F I Y R D Y L I R L R A C I A F V A E W S P K C UniProt | I-TASSER | AlphaFold | HORDE | GeneCards | ORDB
| Odorant | EC50 | Adjusted Top | Antagonist? | Aroma Notes |
|---|---|---|---|---|
| 3-hydroxy-3-methylhexanoic acid | -3.98 1 | 3.3 1 | cumin, sweaty, spicy, animalic | |
| butyric acid | - | 0 2 | sharp, acetic, cheesy, buttery, fruity, dairy, creamy | |
| delta-decalactone | - | 0 2 | coconut, creamy, dairy, fatty, fresh, fruity, lactonic, milky, oily, peach, sweet | |
| diacetyl | - | 0 2 | buttery, caramellic, creamy, pungent, sweet |
1.) Chatelain Pierre, Veithen Alex, Olfactory Receptors involved in the perception of sweat carboxylic acids and the use thereof. WO 2014/191047
2.) Geithe, C.; Andersen, G.; Malki, A.; Krautwurst, D. A butter aroma recombinate activates human class-I odorant receptors. J. Agric. Food Chem. 2015, 63, 9410–9420.