Olfactory Receptor family 11 subfamily A member 1.
Sequence:
10 20 30 40 50 60 70 80 90 100 MEIVSTGNET ITEFVLLGFY DIPELHFLFF IVFTAVYVFI IIGNMLIIVA VVSSQRLHKP MYIFLANLSF LDILYTSAVM PKMLEGFLQE ATISVAGCLL 110 120 130 140 150 160 170 180 190 200 QFFIFGSLAT AECLLLAVMA YDRYLAICYP LHYPLLMGPR RYMGLVVTTW LSGFVVDGLV VALVAQLRFC GPNHIDQFYC DFMLFVGLAC SDPRVAQVTT 210 220 230 240 250 260 270 280 290 300 LILSVFCLTI PFGLILTSYA RIVVAVLRVP AGASRRRAFS TCSSHLAVVT TFYGTLMIFY VAPSAVHSQL LSKVFSLLYT VVTPLFNPVI YTMRNKEVHQ 310 320 ALRKILCIKQ TETLD
Transmembrane Helices:
TMR1 TMR2 TMR3 TMR4 TMR5 TMR6 TMR7 H L E P F G A V S L V R P D V Y F I L L Q S F L F G E L L L C A V V L V Q A M L T V K S F V I F M K P M I F F Q G D V I L T T G Y F T L L S F V A T V A S S G F V F G S V S L T V V V T Y I F V Y T Y L I A T A L L W T T L C F A L H S L P T V G I I D L F L C E T V V L F P I S C T P N F I L M N S L N A V A L L G M Y L I L G S F A R Y I V A V I L F I Y A M R R P G Y S T R R S V V Y M P K L Y R D V I R A A G A P C I A V A V Y R L UniProt | I-TASSER | AlphaFold | HORDE | GeneCards
Odorant | EC50 | Adjusted Top | Antagonist? | Aroma Notes |
---|---|---|---|---|
2-ethyl fenchol | -9 1 | 10 2 | camphoraceous, earthy, humus, mushroom, musty, patchouli, potato, rooty, tea | |
geosmin | -6 3 | 10 3 | earthy, fresh, musty, soil | |
aldehyde C-10 | - | 0 2 | aldehydic, citrus, floral, orange, peel, sweet, waxy | |
aldehyde C-9 | - | 0 2 | aldehydic, fatty, fresh, orange, orris, peel, peely, rose, waxy | |
amyl hexanoate | - | 0 2 | apple, estery, fatty, fruity, green, pear, pineapple, sweet | |
androstenone | - | 0 2 | animal, musky | |
l-arabinose | - | 0 2 | ||
butyl formate | - | 0 2 | brandy, fruity, plum, rummy | |
butyric acid | - | 0 2 | acetic, buttery, cheesy, fruity, sharp | |
(S)-(+)-carvone | - | 0 2 | bready, caraway, minty, spicy | |
citral | - | 0 2 | citrus, lemon, sharp, sweet | |
coumarin | - | 0 2 | coumarinic, hay, sweet, tonka | |
beta-damascone | - | 0 2 | berry, currant, floral, fruity, honey, plum, rose, tobacco | |
ethyl vanillin | - | 0 2 | caramellic, creamy, sweet, vanilla | |
eugenol | - | 0 2 | clove, spicy, sweet, woody | |
eugenyl acetate | - | 0 2 | carnation, clove, floral, fresh, malty, spicy, sweet, woody | |
geranyl acetate | - | 0 2 | floral, green, lavender, rose, waxy | |
helional | - | 0 2 | cyclamen, fresh, green, hay, ozone, watery | |
2-heptanone | - | 0 2 | banana, cheesy, coconut, creamy, fruity, green, herbal, ketonic, spicy, sweet, waxy, woody | |
cis-3-hexen-1-ol | - | 0 2 | foliage, fresh, grassy, green, herbal, oily, vegetable | |
isobutylamine | - | 0 2 | cheesy, fishy | |
d-limonene | - | 0 2 | citrus, fresh, orange, sweet | |
linalool | - | 0 2 | blueberry, bois_de_rose, citrus, floral, green, rose, sweet, woody | |
lyral | - | 0 2 | aquatic, clean, cyclamen, floral, muguet, rhubarb, watery, waxy, woody | |
(+)-menthol | - | 0 2 | cooling, mentholic, minty | |
methyl eugenol | - | 0 2 | carnation, cinnamon, clove, fresh, spicy, sweet, warm | |
methyl furfuryl disulfide | - | 0 2 | alliaceous, coffee, meaty, roasted, sulfurous | |
methyl salicylate | - | 0 2 | minty, wintergreen | |
octanethiol | - | 0 2 | sulfurous | |
1-octanol | - | 0 2 | aldehydic, green, mushroom, orange, rose, waxy | |
octyl octanoate | - | 0 2 | coconut, fruity, oily | |
pelargonic acid | - | 0 2 | cheesy, dairy, dirty, waxy | |
pentanol | - | 0 2 | balsamic, fermented, fusel, oily, sweet | |
propanal | - | 0 2 | alcoholic, cocoa, earthy, nutty, whiskey, winey | |
propionic acid | - | 0 2 | acidic, cheesy, pungent, vinegar | |
pyrazine | - | 0 2 | pungent, sweet, corn, roasted, hazelnut, barley | |
quinoline | - | 0 2 | earthy, medicinal, musty, rubbery, tobacco | |
terpinyl acetate | - | 0 2 | bergamot, citrus, herbal, lavender, lime | |
coffee difuran | - | -0.1667 2 | cabbage, chicken, coffee, meaty, onion, roasted, sulfurous, cocoa, earthy, fungal, mild, mushroom, nutty | |
2,4-DNT | - | -0.3333 2 | ||
benzene | - | -0.5 2 | ||
allyl phenylacetate | - | -0.6667 2 | fruity, honey, rummy | |
dimethyl disulfide | - | -0.6667 2 | cabbage, onion, sulfurous, vegetable |
1.) Dunkel, A.; Steinhaus, M.; Kotthoff, M.; Nowak, B.; Krautwurst, D.; Schieberle, P.; Hofmann, T. Nature’s chemical signatures in human olfaction: A foodborne perspective for future biotechnology. Angew. Chem. Int. Ed. Engl. 2014, 53, 7124–7143.
2.) Adipietro KA, Mainland JD, Matsunami H (2012) Functional Evolution of Mammalian Odorant Receptors. PLoS Genet 8(7): e1002821. doi:10.1371/ journal.pgen.1002821
3.) Aya Kato, Naoko Saito (2017) Search method for mold odor inhibitor JP6104058B2