terrasol, 6-ethyl-1,5,5-trimethylbicyclo[2.2.1]heptan-6-ol
SMILES:
CC1(C2CCC(C2)(C1(O)CC)C)C
Aroma Description:
camphoraceous, earthy, humus, mushroom, musty, patchouli, potato, rooty, tea1
| Receptor | log10 EC50 | Adj. Top | Antagonist? | Correlated Perceptual Qualities |
|---|---|---|---|---|
| OR11A1 | -5 2, -3.98 3, -9 5, -4.9948 6 | 1.1 6 | rooty, tea, patchouli, musty, potato, earthy, camphoraceous | |
| OR7D4 | - | 0.2 4 | animal | |
| OR10G3 | - | 0 3 | ||
| OR10G7 | - | 0 3 | ||
| OR10J5 | - | 0 3 | ||
| OR1C1 | - | 0 3 | ||
| OR2A25 | - | 0 3 | ||
| OR2B11 | - | 0 3 | ||
| OR2J2 | - | 0 3 | ||
| OR2J3 | - | 0 3 | ||
| OR51E1 | - | 0 3 | ||
| OR51L1 | - | 0 3 | ||
| OR56A4 | - | 0 3 | ||
| OR5K1 | - | 0 3 | ||
| OR8K3 | - | 0 3 | ||
| OR8D1 | - | -0.0433 3 | ||
| OR2W1 | - | -1 3 | ||
| OR1A1 | - | -1.6667 3 | ||
| OR5P3 | - | -2.3333 3 |
terrasol, 6-ethyl-1,5,5-trimethylbicyclo[2.2.1]heptan-6-ol
SMILES:
CC1(C2CCC(C2)(C1(O)CC)C)C
Aroma Description:
camphoraceous, earthy, humus, mushroom, musty, patchouli, potato, rooty, tea
| Receptor | Dock Score | Affinity | A100 | Correlated Perceptual Qualities |
|---|
Dock Score: This is a measure of whether the algorithm thinks the odorant is an agonist of the receptor.
Affinity: The binding affinity, in kJ/mol, of the ligand docked in the active or inactive model, whichever is greater.
A100: A measure of the degree of activation of the receptor. See
Ibrahim et al (2019).
1.) The Good Scents Company
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3.) Adipietro KA, Mainland JD, Matsunami H (2012) Functional Evolution of Mammalian Odorant Receptors. PLoS Genet 8(7): e1002821. doi:10.1371/ journal.pgen.1002821
4.) Keller A, Zhuang H, Chi Q, Vosshall LB, Matsunami H. Genetic variation in a human odorant receptor alters odour perception. Nature. 2007 Sep 27;449(7161):468-72. doi: 10.1038/nature06162. Epub 2007 Sep 16. PMID: 17873857.
5.) Dunkel, A.; Steinhaus, M.; Kotthoff, M.; Nowak, B.; Krautwurst, D.; Schieberle, P.; Hofmann, T. Nature’s chemical signatures in human olfaction: A foodborne perspective for future biotechnology. Angew. Chem. Int. Ed. Engl. 2014, 53, 7124–7143.
6.) Lena Ball, Tim Frey, Franziska Haag, Stephanie Frank, Sandra Hoffmann, Matthias Laska, Martin Steinhaus, Klaus Neuhaus, and Dietmar Krautwurst Geosmin, a Food- and Water-Deteriorating Sesquiterpenoid and Ambivalent Semiochemical, Activates Evolutionary Conserved Receptor OR11A1 Journal of Agricultural and Food Chemistry Article ASAP