propanoic acid
SMILES:
CCC(=O)[O-]
Aroma Description:
acidic, cheesy, pungent, vinegar1
| Receptor | log10 EC50 | Adj. Top | Antagonist? | Correlated Perceptual Qualities |
|---|---|---|---|---|
| OR51E2 | -3 2, -3.96 6, -3.6 7, -3 10 | 0.4844 2, 9 6, 10 7, 3.4 10 | vinegar, sour, sharp, radish | |
| OR51E1 | -4.97 5 | - | cheesy, sweaty, sour, acidic | |
| OR52D1 | - | 2.5381 3 | anise, cheesy, orange, sweet, dairy, sour, rancid, waxy, tart, sharp | |
| OR12D2 | - | 1.9231 8 | vinegar, sour | |
| OR1G1 | - | 0.5076 3 | waxy, tart, orange, sweet, aldehydic, fresh, citrus, clean, medicinal, anise | |
| OR10G3 | - | 0 4 | ||
| OR10G7 | - | 0 4 | ||
| OR10J5 | - | 0 4, 0 6 | ||
| OR11A1 | - | 0 4 | ||
| OR1C1 | - | 0 4 | ||
| OR2A25 | - | 0 4 | ||
| OR2B11 | - | 0 4 | ||
| OR2J2 | - | 0 4, 0 6 | ||
| OR2J3 | - | 0 4 | ||
| OR2W1 | - | 0 4, 0 6 | ||
| OR51L1 | - | 0 4, 0 6 | ||
| OR56A4 | - | 0 4 | ||
| OR5K1 | - | 0 4 | ||
| OR5P3 | - | 0 4, 0 6 | ||
| OR8D1 | - | 0 4 | ||
| OR8K3 | - | 0 4 | ||
| OR2C1 | - | 0 6 | ||
| OR5I1 | - | 0 8 | ||
| OR1A1 | - | -1.2333 4, 0 6 |
propanoic acid
SMILES:
CCC(=O)[O-]
Aroma Description:
acidic, cheesy, pungent, vinegar
Dock Score: This is a measure of whether the algorithm thinks the odorant is an agonist of the receptor.
Affinity: The binding affinity, in kJ/mol, of the ligand docked in the active or inactive model, whichever is greater.
A100: A measure of the degree of activation of the receptor. See
Ibrahim et al (2019).
1.) The Good Scents Company
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9.) Halperin Kuhns, V. L., Sanchez, J., Sarver, D. C., Khalil, Z., Rajkumar, P., Marr, K. A., & Pluznick, J. L. (2019). Characterizing novel olfactory receptors expressed in the murine renal cortex. American Journal of Physiology-Renal Physiology, 317(1), F172-F186.
10.) Christian B. Billesbølle, Claire A. de March, Wijnand J. C. van der Velden, Ning Ma, Jeevan Tewari, Claudia Llinas del Torrent, Linus Li, Bryan Faust, Nagarajan Vaidehi, Hiroaki Matsunami, Aashish Manglik. Structural basis of odorant recognition by a human odorant receptor. bioRxiv 2022.12.20.520951; doi: https://doi.org/10.1101/2022.12.20.520951